AAV Capsids Developed at the University of Florida
| AAV serotype/variant | Capsid mutations | Cell tropism | References |
|---|---|---|---|
| AAV1 | — | RPE, Muscle | Burger et al. |
| AAV1 (E531K) | — | — | — |
| AAV2 | — | Liver, RPE, RGC | Acland et al.; Guy et al. |
| AAV2 (QuadY-F+T-V), aka Y272F+Y444F+Y500F+Y730F+T491V) | — | — | — |
| AAV2 (Y444F) | — | — | — |
| AAV2 (Trp YF, aka Y444F+Y500F+Y730F) | — | — | — |
| AAV2 (4pMut) dHS | — | — | — |
| AAV2 retrohelper | — | — | — |
| AAV2 (Trp Mut) | — | — | — |
| AAV4 | — | — | — |
| AAV5 | — | PR, RPE, Cornea, Brain | Boye et al.; Beltran et al.; Mohan et al.; Burger et al. |
| AAV6 | — | HSCs, glia | Song et al. |
| AAV6-TrpMut, aka Y705F+Y731F+T492V | Y705+731F+T492V | HSCs, glia | Rosario et al. |
| AAV8 | — | PR | Allocca et al. |
| AAV8 (Y733F) | Y733F | PR, RPE | Petrs-Silva et al.; Pang et al.; Boye et al., Deng et al. |
| AAV8-TrpMut, aka Y447F+Y733F+T494V | Y447F | PR | Petrs-Silva et al. |
| AAV9 | — | PR, Liver, Heart | Lebherz et al.; Sarkar et al. |
| AAVRh10, rh74 | –– | –– | –– |
| AAV44.9 | –– | –– | –– |
| AAV44.9 (E531D) | –– | –– | –– |
| AAVP2V1, AAVP2V3 | –– | –– | –– |
| AAV PHP.B | –– | –– | –– |
| AAVPHP.S | –– | –– | –– |
| AAV DGEDF | –– | –– | –– |